GPCRs, class A rhodopsin-like (WP473)

Rattus norvegicus

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This pathway was created using the GPCRDB (Horn et al., 1998), http://www.gpcr.org/7tm/ (originally at http://www.cmbi.kun.nl/7tm/). The groupings are based on the GPCR phylogenetic tree available from the GPCRDB and the training sets used by Karchin et al. (Bioinformatics, 2002, pg. 147-159). The labels indicate children and grandchildren of the various classes of GPCRs as described by these references.

Authors

Christine Chichester , Egon Willighagen , Denise Slenter , Eric Weitz , and Alex Pico

Activity

last edited

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Organisms

Rattus norvegicus

Communities

Annotations

Pathway Ontology

G protein mediated signaling pathway

Participants

Label Type Compact Identifier Comment
Dopamine Metabolite chebi:18243
Bradykinin Metabolite chebi:3165
Prostaglandin Metabolite chebi:26333
Serotonin Metabolite chebi:28790
Angiotensin II Metabolite hmdb:HMDB0001035
Histamine Metabolite chebi:18295
Olr1467 GeneProduct ncbigene:287481
Rrh GeneProduct ncbigene:310869
Xcr1 GeneProduct ncbigene:301086
Ccr4 GeneProduct ncbigene:171054
Drd2 GeneProduct ncbigene:24318
Gpr52 GeneProduct ncbigene:680192
MC1R GeneProduct ncbigene:292083
P2ry10 GeneProduct ncbigene:317219
Oprm1 GeneProduct ncbigene:25601
F2rl1 GeneProduct ncbigene:116677
P2ry4 GeneProduct ncbigene:63843
Htr2b GeneProduct ncbigene:29581
Cysltr2 GeneProduct ncbigene:170926
Mtnr1b GeneProduct ncbigene:192646
Htr1f GeneProduct ncbigene:60448
Olr1730 GeneProduct ncbigene:294187
Cnr1 GeneProduct ncbigene:25248
Gpr85 GeneProduct ncbigene:64020
Cxcr5 GeneProduct ncbigene:29363
LOC685243 GeneProduct ncbigene:685243
GPR17 GeneProduct ncbigene:767613
P2ry6 GeneProduct ncbigene:117264
Galr2 GeneProduct ncbigene:29234
Sstr5 GeneProduct ncbigene:25354
Olr1086 GeneProduct ncbigene:299588
NTSR2 GeneProduct ncbigene:64636
Cx3cr1 GeneProduct ncbigene:171056
Gpr15 GeneProduct ncbigene:288181
Gpr37l1 GeneProduct ncbigene:252939
Sstr4 GeneProduct ncbigene:25555
GPR6 GeneProduct ncbigene:83683
Olr1201 GeneProduct ncbigene:405106
P2ry2 GeneProduct ncbigene:29597
Lpar5 GeneProduct ncbigene:500317
GPR39 GeneProduct ncbigene:288995
Sstr2 GeneProduct ncbigene:54305
Drd4 GeneProduct ncbigene:25432
Olr1075 GeneProduct ncbigene:299596
Ccr8 GeneProduct ncbigene:301066
Chrm2 GeneProduct ncbigene:81645
Hcrtr1 GeneProduct ncbigene:25593
Oprl1 GeneProduct ncbigene:29256
Cxcr3 GeneProduct ncbigene:84475
Mtnr1a GeneProduct ncbigene:114211
OPN1MW GeneProduct ncbigene:89810
Fpr1 GeneProduct ncbigene:292409
Oprk1 GeneProduct ncbigene:29335
F2RL3 GeneProduct ncbigene:116498
Ptger1 GeneProduct ncbigene:25637
Ptger4 GeneProduct ncbigene:84023
Rgr GeneProduct ncbigene:306307
Ptgfr GeneProduct ncbigene:25652
Olr836 GeneProduct ncbigene:298394
Cnr2 GeneProduct ncbigene:57302
ADRA2A GeneProduct ncbigene:25083
Htr4 GeneProduct ncbigene:25324
Olr231 GeneProduct ncbigene:293375
Adora1 GeneProduct ncbigene:29290
Nmbr GeneProduct ncbigene:25264
Nmur2 GeneProduct ncbigene:64042
Trhr GeneProduct ncbigene:25570
Opn4 GeneProduct ncbigene:192223
Htr1b GeneProduct ncbigene:25075
Gpr19 GeneProduct ncbigene:312787
Gpr22 GeneProduct ncbigene:298944
Rho GeneProduct ncbigene:24717
F2r GeneProduct ncbigene:25439
Adora2a GeneProduct ncbigene:25369
Fpr2 GeneProduct ncbigene:690158
Olr1073 GeneProduct ncbigene:405362
Sstr1 GeneProduct ncbigene:25033
Cmklr1 GeneProduct ncbigene:60669
Nmur1 GeneProduct ncbigene:65276
Adra2c GeneProduct ncbigene:24175
Adora3 GeneProduct ncbigene:25370
Gpr31 GeneProduct ncbigene:292310
Ffar3 GeneProduct ncbigene:365228
Mchr1 GeneProduct ncbigene:83567
RGD1563245 GeneProduct ncbigene:289180
Ptafr GeneProduct ncbigene:58949
GALR1 GeneProduct ncbigene:50577
Agtr1a GeneProduct ncbigene:24180
Chrm4 GeneProduct ncbigene:25111
Olr1662 GeneProduct ncbigene:291361
Ptger2 GeneProduct ncbigene:81752
Olr1750 GeneProduct ncbigene:294204
Oxtr GeneProduct ncbigene:25342
Olr464 GeneProduct ncbigene:295734
Hcrtr2 GeneProduct ncbigene:25605
Gpr37 GeneProduct ncbigene:117549
Gpr173 GeneProduct ncbigene:64021
Adra1b GeneProduct ncbigene:24173
Gpr34 GeneProduct ncbigene:554353
Gpr50 GeneProduct ncbigene:117097
Lhcgr GeneProduct ncbigene:25477
P2ry1 GeneProduct ncbigene:25265
Htr5a GeneProduct ncbigene:25689
Olr227 GeneProduct ncbigene:293370
Adrb1 GeneProduct ncbigene:24925
Gpr68 GeneProduct ncbigene:314386
Htr6 GeneProduct ncbigene:64354
Ptger3 GeneProduct ncbigene:24929
Ltb4r GeneProduct ncbigene:59264
NPY1R GeneProduct ncbigene:29358
Olr226 GeneProduct ncbigene:65140
Gpr65 GeneProduct ncbigene:299242
Gpr35 GeneProduct ncbigene:367315
Gpr1 GeneProduct ncbigene:25457
P2ry13 GeneProduct ncbigene:310444
Olr1693 GeneProduct ncbigene:365523
Ccr3 GeneProduct ncbigene:117027
Grpr GeneProduct ncbigene:24938
Htr1a GeneProduct ncbigene:24473
Olr808 GeneProduct ncbigene:405140
Il8rb GeneProduct ncbigene:29385
Olr1654 GeneProduct ncbigene:60451
Gpr174 GeneProduct ncbigene:302373
Drd3 GeneProduct ncbigene:29238
Npffr2 GeneProduct ncbigene:78964
Olr1329 GeneProduct ncbigene:405075
Gpr63 GeneProduct ncbigene:297952
Ptgir GeneProduct ncbigene:292661
Opn3 GeneProduct ncbigene:498289
Npbwr1 GeneProduct ncbigene:297795
Prlhr GeneProduct ncbigene:246075
Gpr45 GeneProduct ncbigene:301372
Ccrl2 GeneProduct ncbigene:316019
Opn1sw GeneProduct ncbigene:81644
Gpr81 GeneProduct ncbigene:689936
Olr1512 GeneProduct ncbigene:287511
Ccr6 GeneProduct ncbigene:308163
Fshr GeneProduct ncbigene:25449
GPR77 GeneProduct ncbigene:445269
Avpr1b GeneProduct ncbigene:29462
Il8ra GeneProduct ncbigene:54258
P2ry14 GeneProduct ncbigene:171108
Gpr3 GeneProduct ncbigene:266769
Olr1579 GeneProduct ncbigene:289239
Fpr3 GeneProduct ncbigene:292413
Oprd1 GeneProduct ncbigene:24613
Hrh3 GeneProduct ncbigene:85268
Gpr44 GeneProduct ncbigene:309212
Lpar4 GeneProduct ncbigene:302378
Adora2b GeneProduct ncbigene:29316
F2rl2 GeneProduct ncbigene:29636
Olr1671 GeneProduct ncbigene:294138
Olr588 GeneProduct ncbigene:295822
Ffar1 GeneProduct ncbigene:266607
Ccbp2 GeneProduct ncbigene:140473
Cckbr GeneProduct ncbigene:25706
Npy5r GeneProduct ncbigene:25340
Adrb3 GeneProduct ncbigene:25645
Adra1a GeneProduct ncbigene:29412
Cxcr7 GeneProduct ncbigene:84348
Ffar2 GeneProduct ncbigene:292794
Olr1077 GeneProduct ncbigene:405280
Gpr87 GeneProduct ncbigene:310443
Galr3 GeneProduct ncbigene:29235
Htr2a GeneProduct ncbigene:29595
Chrm3 GeneProduct ncbigene:24260
Brs3 GeneProduct ncbigene:260319
Ednra GeneProduct ncbigene:24326
Olr1517 GeneProduct ncbigene:287516
CCR2 GeneProduct ncbigene:60463
Olr1606 GeneProduct ncbigene:305711
Aplnr GeneProduct ncbigene:83518
Mc2r GeneProduct ncbigene:282839
Drd5 GeneProduct ncbigene:25195
Gpr21 GeneProduct ncbigene:689917
P2ry5 GeneProduct ncbigene:691774
Tbxa2r GeneProduct ncbigene:24816
Adrb2 GeneProduct ncbigene:24176
Adra1d GeneProduct ncbigene:29413
Sucnr1 GeneProduct ncbigene:408199
Mc3r GeneProduct ncbigene:29310
PTGDR GeneProduct ncbigene:498475
Cysltr1 GeneProduct ncbigene:114099
Gper GeneProduct ncbigene:171104
Gpr4 GeneProduct ncbigene:308408
Adra2b GeneProduct ncbigene:24174
Gpr20 GeneProduct ncbigene:60667
Ccr1 GeneProduct ncbigene:57301
Ntsr1 GeneProduct ncbigene:366274
Agtr2 GeneProduct ncbigene:24182
C3ar1 GeneProduct ncbigene:84007
Mc4r GeneProduct ncbigene:25635
Avpr2 GeneProduct ncbigene:25108
Gpr27 GeneProduct ncbigene:65275
Chrm1 GeneProduct ncbigene:25229
Hrh1 GeneProduct ncbigene:24448
Ppyr1 GeneProduct ncbigene:29471
Avpr1a GeneProduct ncbigene:25107
Ccr10 GeneProduct ncbigene:363682
Ghsr GeneProduct ncbigene:84022
Olr217 GeneProduct ncbigene:293364
Olr806 GeneProduct ncbigene:405331
Npffr1 GeneProduct ncbigene:64107
Htr7 GeneProduct ncbigene:65032
Hrh2 GeneProduct ncbigene:25461
P2ry12 GeneProduct ncbigene:64803
Htr2c GeneProduct ncbigene:25187
Gpr171 GeneProduct ncbigene:688737
Olr420 GeneProduct ncbigene:296682
Mas1 GeneProduct ncbigene:25153
Mc5r GeneProduct ncbigene:25726
Drd1a GeneProduct ncbigene:24316
Gpr18 GeneProduct ncbigene:679957
Cckar GeneProduct ncbigene:24889
Opn1mw GeneProduct ncbigene:89810
Ednrb GeneProduct ncbigene:50672
Bdkrb1 GeneProduct ncbigene:81509
Olr1743 GeneProduct ncbigene:294197
Olr1466 GeneProduct ncbigene:287480
Bdkrb2 GeneProduct ncbigene:25245
Olr1356 GeneProduct ncbigene:302954
Gpr83 GeneProduct ncbigene:140595
Npy2r GeneProduct ncbigene:66024
Sstr3 GeneProduct ncbigene:171044
Htr1d GeneProduct ncbigene:25323
Olr811 GeneProduct ncbigene:405138
Cxcr4 GeneProduct ncbigene:60628
Gpr75 GeneProduct ncbigene:498434
Ccr5 GeneProduct ncbigene:117029
Gpcr12 GeneProduct ncbigene:80840
Ccr7 GeneProduct ncbigene:287673
Gpr25 GeneProduct ncbigene:363993
Ccr9 GeneProduct ncbigene:282832
Olr1749 GeneProduct ncbigene:294203
Olr1087 GeneProduct ncbigene:299586
Chrm5 GeneProduct ncbigene:53949

References