Thermogenesis (WP4321)

Homo sapiens

Open in new tab Open in NDEx
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
Thermogenesis is an essential process of heat production in warm-blooded animals and some plants.

Authors

Kristina Hanspers , Egon Willighagen , and Friederike Ehrhart

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Homo sapiens

Communities

Annotations

Cell Type Ontology

beige adipocyte brown fat cell

Pathway Ontology

electron transport chain pathway

Participants
Query Drugst.One

Label Type Compact Identifier Comment
ADP Metabolite chebi:16761
2-Arachidonoylglycerol Metabolite chebi:52392
Glycerol Metabolite chebi:17754
cAMP Metabolite chebi:17489
Coenzyme A Metabolite chebi:15346
NADH Metabolite chebi:16908
Carnitine Metabolite chebi:3424
Nicotine Metabolite chebi:17688
Acyl-CoA Metabolite chebi:17984
MG Metabolite chebi:35759
Arachidonylethanolamide Metabolite chebi:2700
Acylcarnitine Metabolite chebi:75659
H+ Metabolite chebi:15378
Acetyl-CoA Metabolite hmdb:HMDB0001206
3,3',5'-Triiodothyronine Metabolite chebi:11684
TG Metabolite chebi:75844
cGMP Metabolite chebi:16356
Estradiol-17beta Metabolite chebi:16469
H+ Metabolite chebi:15378
FADH2 Metabolite chebi:17877
ANP Metabolite chebi:80233
DG Metabolite chebi:18035
L-noradrenaline Metabolite chebi:18357
fatty acid Metabolite chebi:35366
BNP Metabolite chebi:80234
fatty acid Metabolite chebi:35366
ATP Metabolite chebi:15422
Acyl-CoA Metabolite chebi:17984
Acylcarnitine Metabolite chebi:75659
Coenzyme A Metabolite chebi:15346
Carnitine Metabolite chebi:3424
H+ Metabolite chebi:15378
H+ Metabolite chebi:15378
H+ Metabolite chebi:15378
H+ Metabolite chebi:15378
H+ Metabolite chebi:15378
Endocannabinoids Metabolite wikidata:Q55282178
BMP8A GeneProduct ensembl:ENSG00000183682
PRDM16 GeneProduct ensembl:ENSG00000142611
PLIN1 GeneProduct ensembl:ENSG00000166819
SLC25A20 GeneProduct ensembl:ENSG00000178537
RHEB GeneProduct ensembl:ENSG00000106615
RPTOR GeneProduct ensembl:ENSG00000141564
ZNF516 GeneProduct ensembl:ENSG00000101493
FGF21 GeneProduct ensembl:ENSG00000105550
KDM3B GeneProduct ensembl:ENSG00000120733
GRB2 GeneProduct ensembl:ENSG00000177885
PPARGC1A GeneProduct ensembl:ENSG00000109819
PRKAG2 GeneProduct ensembl:ENSG00000106617
PRKG1 GeneProduct ensembl:ENSG00000185532
RPS6KA1 GeneProduct ensembl:ENSG00000117676
CPT1A GeneProduct ensembl:ENSG00000110090
FRS2 GeneProduct ensembl:ENSG00000166225
ARID1B GeneProduct ensembl:ENSG00000049618
TSC1 GeneProduct ensembl:ENSG00000165699
PNPLA2 GeneProduct ensembl:ENSG00000177666
RPS6KB1 GeneProduct ensembl:ENSG00000108443
CREB3 GeneProduct ensembl:ENSG00000107175
UCP1 GeneProduct ensembl:ENSG00000109424
RPS6KA6 GeneProduct ensembl:ENSG00000072133
MGLL GeneProduct ensembl:ENSG00000074416
FGF21 GeneProduct ensembl:ENSG00000105550
ADRB3 GeneProduct ensembl:ENSG00000188778
PRKAG3 GeneProduct ensembl:ENSG00000115592
KDM1A GeneProduct ensembl:ENSG00000004487
MAP3K5 GeneProduct ensembl:ENSG00000197442
UCP1 GeneProduct ensembl:ENSG00000109424
SLC25A29 GeneProduct ensembl:ENSG00000197119
ATF2 GeneProduct ensembl:ENSG00000115966
PPARG GeneProduct ensembl:ENSG00000132170
ACSL1 GeneProduct ensembl:ENSG00000151726
SIRT6 GeneProduct ensembl:ENSG00000077463
GNAS GeneProduct ensembl:ENSG00000087460
HRAS GeneProduct ensembl:ENSG00000174775
CPT2 GeneProduct ensembl:ENSG00000157184
PRKACA GeneProduct ensembl:ENSG00000072062
RPS6KA2 GeneProduct ensembl:ENSG00000071242
ACTL6B GeneProduct ensembl:ENSG00000077080
RPS6 GeneProduct ensembl:ENSG00000137154
RPS6KA3 GeneProduct ensembl:ENSG00000177189
GCG GeneProduct ensembl:ENSG00000115263
ADCY1 GeneProduct ensembl:ENSG00000164742
ADCY2 GeneProduct ncbigene:108
ADCY3 GeneProduct ncbigene:109
ADCY5 GeneProduct ensembl:ENSG00000173175
ADCY6 GeneProduct ensembl:ENSG00000174233
ADCY7 GeneProduct ensembl:ENSG00000121281
ADCY8 GeneProduct ensembl:ENSG00000155897
ADCY9 GeneProduct ensembl:ENSG00000162104
ADCY4 GeneProduct ensembl:ENSG00000129467
ADCY10 GeneProduct ensembl:ENSG00000143199
CNR1 GeneProduct ensembl:ENSG00000118432
NPR1 GeneProduct ensembl:ENSG00000169418
KLB GeneProduct ensembl:ENSG00000134962
FGFR1 GeneProduct ensembl:ENSG00000077782
SOS1 GeneProduct ensembl:ENSG00000115904
SOS2 GeneProduct ensembl:ENSG00000100485
KRAS GeneProduct ensembl:ENSG00000133703
NRAS GeneProduct ensembl:ENSG00000213281
TSC2 GeneProduct ensembl:ENSG00000103197
MTOR GeneProduct ensembl:ENSG00000198793
MLST8 GeneProduct ensembl:ENSG00000167965
AKT1S1 GeneProduct ensembl:ENSG00000204673
RPS6KB2 GeneProduct ensembl:ENSG00000175634
PRKG2 GeneProduct ensembl:ENSG00000138669
LIPE GeneProduct ensembl:ENSG00000079435
PRKACB GeneProduct ensembl:ENSG00000142875
PRKACG GeneProduct ensembl:ENSG00000165059
MAP2K3 GeneProduct ensembl:ENSG00000034152
MAPK14 GeneProduct ensembl:ENSG00000112062
MAPK11 GeneProduct ensembl:ENSG00000185386
MAPK13 GeneProduct ensembl:ENSG00000156711
MAPK12 GeneProduct ensembl:ENSG00000188130
CREB1 GeneProduct ensembl:ENSG00000118260
CREB3L4 GeneProduct ensembl:ENSG00000143578
CREB3L2 GeneProduct ensembl:ENSG00000182158
CREB3L3 GeneProduct ensembl:ENSG00000060566
CREB3L1 GeneProduct ncbigene:90993
CREB5 GeneProduct ensembl:ENSG00000146592
KDM3A GeneProduct ensembl:ENSG00000115548
ACTB GeneProduct ensembl:ENSG00000075624
SMARCA2 GeneProduct ensembl:ENSG00000080503
SMARCA4 GeneProduct ensembl:ENSG00000127616
SMARCB1 GeneProduct ensembl:ENSG00000099956
SMARCC1 GeneProduct ensembl:ENSG00000173473
SMARCC2 GeneProduct ensembl:ENSG00000139613
SMARCD1 GeneProduct ensembl:ENSG00000066117
SMARCD2 GeneProduct ensembl:ENSG00000108604
SMARCD3 GeneProduct ensembl:ENSG00000082014
SMARCE1 GeneProduct ensembl:ENSG00000073584
ACTG1 GeneProduct ensembl:ENSG00000184009
DPF3 GeneProduct ensembl:ENSG00000205683
DPF1 GeneProduct ensembl:ENSG00000011332
ARID1A GeneProduct ensembl:ENSG00000117713
ACTL6A GeneProduct ensembl:ENSG00000136518
UCP1 GeneProduct ensembl:ENSG00000109424
ACSL3 GeneProduct ensembl:ENSG00000123983
ACSL4 GeneProduct ensembl:ENSG00000068366
ACSL5 GeneProduct ensembl:ENSG00000197142
ACSL6 GeneProduct ensembl:ENSG00000164398
CPT1B GeneProduct ensembl:ENSG00000205560
CPT1C GeneProduct ensembl:ENSG00000169169
PRKAA1 GeneProduct ensembl:ENSG00000132356
PRKAA2 GeneProduct ensembl:ENSG00000162409
PRKAB1 GeneProduct ensembl:ENSG00000111725
PRKAB2 GeneProduct ensembl:ENSG00000131791
PRKAG1 GeneProduct ensembl:ENSG00000181929
BMP8B GeneProduct ensembl:ENSG00000116985

References