Phase I biotransformations, non P450 (WP1291)

Rattus norvegicus

Open in new tab
Download PNG Download SVG Download JSON Download GPML Learn more about Downloads
This pathway lists several phase 1 biotransformations and their related enzymes.

Authors

Daniela Digles , Kristina Hanspers , Martina Summer-Kutmon , and Lars Willighagen

Activity

last edited

Discuss this pathway

Check for ongoing discussions or start your own.

Cited In

Are you planning to include this pathway in your next publication? See How to Cite and add a link here to your paper once it's online.

Organisms

Rattus norvegicus

Communities

Annotations

Pathway Ontology

cytochrome P450-independent phase I biotransformation pathway

Participants

Label Type Compact Identifier Comment
thio esters Metabolite chebi:51277
Phosphoric acid esters Metabolite chebi:37734
thio esters Metabolite chebi:51277
carboxylic acid esters Metabolite chebi:33308
amides Metabolite chebi:32988
carboxylic acid esters Metabolite chebi:33308
Phosphoric acid esters Metabolite chebi:37734
amides Metabolite chebi:32988
Ces5a GeneProduct ensembl:ENSRNOG00000025710 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000159398
Esd GeneProduct ensembl:ENSRNOG00000009512 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000139684
Lipa GeneProduct ensembl:ENSRNOG00000019077 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000107798
Pon3 GeneProduct ensembl:ENSRNOG00000009096 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105852
Ces2j GeneProduct ensembl:ENSRNOG00000029744 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000172831
Pon2 GeneProduct ensembl:ENSRNOG00000009112 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000105854
Ces1a GeneProduct ensembl:ENSRNOG00000039725 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000198848
Pon1 GeneProduct ensembl:ENSRNOG00000008902 Homology Mapping from Homo sapiens to Rattus norvegicus: Original ID = En:ENSG00000005421

References

  1. Casarett & Doull’s Essentials of Toxicology [Internet]. Klaassen C, Watkins JB III. McGraw-Hill Professional; 2003. 548 p. Available from: https://books.google.com/books/about/Casarett_Doull_s_Essentials_of_Toxicolog.html?hl=&id=pj5iQgAACAAJ OpenLibrary Worldcat